Ethyl 3-phenylpropionate is used as an active pharmaceutical ingredient intermediate. It is also used in the synthesis of pyrimidine based inhibitors of cyclin-dependant kinases.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Ethyl 3-phenylpropionate is used as an active pharmaceutical ingredient intermediate. It is also used in the synthesis of pyrimidine based inhibitors of cyclin-dependant kinases.
Solubility
Miscible with oils and ethanol. Immiscible with water.
Notes
Store in a cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Tellitu, I.; Beitia, I.; Díaz, M.; Alonso, A.; Moreno, I.; Domínguez, E. An improved solvent-free system for the microwave-assisted decarboxylation of malonate derivatives based on the use of imidazole. Tetrahedron 2015, 71 (43), 8251-8255.
- Zhang, B.; Lv, C.; Li, W.; Cui, Z.; Chen, D.; Cao, F.; Miao, F.; Zhou, L. Ethyl Cinnamate Derivatives as Promising High-Efficient Acaricides against Psoroptes cuniculi: Synthesis, Bioactivity and Structure-Activity Relationship. Chem. Pharm. Bull. 2015, 63 (4), 255-262.