2-Iodobenzoic Acid, methyl ester; 2-Iodobenzoic Acid is a starting material for the preparation of iodosobenzoate, selectivity and environment management. Trivalent iodine compounds perform mild oxidations, oxidative couplings, special iodinations and acetoxylations. Iodobenzoates are used as anti-infective, contraceptive agent and x-ray contrast medium for diagnostic radiology.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Iodobenzoic Acid, methyl ester; 2-Iodobenzoic Acid is a starting material for the preparation of iodosobenzoate, selectivity and environment management. Trivalent iodine compounds perform mild oxidations, oxidative couplings, special iodinations and acetoxylations. Iodobenzoates are used as anti-infective, contraceptive agent and x-ray contrast medium for diagnostic radiology.
Solubility
Insoluble in water.
Notes
Light sensitive. Store at room temperature. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Ronald Grigg.; Tossapol Khamnaen.; Shuleewan Rajviroongit.; Visuvanathar Sridharan. Synthesis of N-substituted 4-methylene-3,4-dihydro-1(2H)-isoquinolin-1-ones via a palladium-catalysed three-component process. Tetrahedron Lett. 2002, 43 (14),2601-2603 .
- Esther C.Y. Woon.; Archana Dhami.; Mary F. Mahon.; Michael D. Threadgill. 5-Nitroisocoumarins from tandem Castro-Stephens coupling—6-endo-dig cyclisation of 2-iodo-3-nitrobenzoic acid and arylethynes and ring-closure of methyl 2-alkynyl-3-nitrobenzoates with electrophiles .Tetrahedron. 2006, 62 (20),4829-4837 .
- For Pd-catalyzed annulation to give an isocoumarin, see 4,4-Dimethyl-2-pentyne, L10210.