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2-Iodophenol, 98%, Thermo Scientific Chemicals
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Catalog number A13599.14
also known as A13599-14
Price (USD)/ Each
119.00
-
Quantity:
25 g
Price (USD)/ Each
119.00
2-Iodophenol, 98%, Thermo Scientific Chemicals
Catalog numberA13599.14
Price (USD)/ Each
119.00
-
Chemical Identifiers
CAS533-58-4
Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder or lumps or fused solid
Melting Point (clear melt)35.0-44.0°C
Identification (FTIR)Conforms
Appearance (Color)White to grey or cream to pink to dark brown
Assay (GC)≥97.5%
2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield.
Solubility
Soluble in water.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. It is sensitive to light. Incompatible with oxidizing agents.
2-Iodophenol is used in the synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity and 3,3-disubstituted-2,3-dihydrobenzofurans. Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield.
Solubility
Soluble in water.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. It is sensitive to light. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Kazumi Okuro.; Howard Alper. Palladium-Catalyzed Carbonylation of o-Iodophenols with Allenes. J. Org. Chem. 1997, 62 (6), 1566-1567.
- Maurizio Botta.; Vincenzo Summa.; Federico Corelli.; Giovanna Di Pietro.; Paolo Lombardi. Synthesis of aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity via palladium-catalyzed heteroannulation of chiral arylpropargylic alcohols. Tetrahedron: Asymmetry. 1996, 7 (5), 1263-1266.
- Coupling with phenylacetylene in the presence of a Pd complex and CuI gives 2-phenylbenzofuran in good yield: Synlett, 515 (1992); J. Chem. Soc., Perkin 1, 2815 (1997):