2-Butyne is used to synthesize alkylated hydroquinones in the total synthesis of Vitamin E. It is also used as pharmaceutical intermediates.
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Applications
2-Butyne is used to synthesize alkylated hydroquinones in the total synthesis of Vitamin E. It is also used as pharmaceutical intermediates.
Solubility
Not miscible in water.
Notes
Avoid extremes of temperature and direct sunlight. Heat-sensitive. Avoid contact with oxidizing materials. Incompatible with Halogens. Chlorinated solvents.
RUO – Research Use Only
Dongmin Shen; Lovat V.C Rees. Adsorption and diffusion of n-butane and 2-butyne in silicalite-I. Zeolites.1991, 11 684-689.
Kevin C. Wallace; Andy H. Liu; William M. Davis; Richard R. Schrock. Living polymerization of 2-butyne using a well-characterized tantalum catalyst.Organometallics.1989, 8 (3), 644-654.
With AlCl3, dimerizes to give the complex of the otherwise unstable tetramethylcyclobutadiene, cycloaddition of which with dimethyl acetylenedicarboxylate gives a Dewar benzene: Synthesis, 139 (1971):
With a catalytic amount of AlCl3, hexamethyl Dewar benzene can be produced directly, with the 2-butyne also acting as the dienophile component: Org. Synth. Coll., 7, 256 (1990).
Reacts with chlorine to give 3,4-dichloro,1,2,3,4-tetramethylcyclobutene, a precursor of various cyclobutadienyl complexes: Org. Synth. Coll., 5, 370 (1973).
For use in formation of a Zr metallocycle as an intermediate in the formation of phospholes and analogous heterocycles, see Bis(cyclopentadienyl)zirconium dichloride, 12548.