The sulfonation of 4-pentenoic acid (Allylacetic acid) yields the corresponding γ-lactone. It was used to inhibit fatty acid oxidation in rat heart mitochondria.
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Applications
The sulfonation of 4-pentenoic acid (Allylacetic acid) yields the corresponding γ-lactone. It was used to inhibit fatty acid oxidation in rat heart mitochondria.
Solubility
Soluble in alcohol, Slightly soluble in water
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and bases.
RUO – Research Use Only
J.C.Fong; H.Schulz. On the rate-determining step of fatty acid oxidation in heart. Inhibition of fatty acid oxidation by 4-pentenoic acid. Journal of Biological Chemistry. 1978, 253,(19), 6917-6922.
C.Corredor; K.Brendel; R.Bressler. Studies of the mechanism of the hypoglycemic action of 4-pentenoic acid. Proc Natl Acad Sci U S A. 1967, 58,(6), 2299-2306.