D-Mannitol is used in the determination of glomerular filtration rate. It is used as an inert osmotic control substance. Further, it is used in the treatment of oliguric renal failure. It is also used as a sweetener for people with diabetes, in chewing gums and acts as an adulterant for heroin, methamphetamines and cocaine. It finds application as a research tool in cell biological studies, usually to control osmolarity.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
D-Mannitol is used in the determination of glomerular filtration rate. It is used as an inert osmotic control substance. Further, it is used in the treatment of oliguric renal failure. It is also used as a sweetener for people with diabetes, in chewing gums and acts as an adulterant for heroin, methamphetamines and cocaine. It finds application as a research tool in cell biological studies, usually to control osmolarity.
Solubility
Soluble in water, alcohol, aniline, pyridine and glycerol. Insoluble in ether.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Wang, C.; Dong, L.; Niu, M.; Liu, M.; Sun, D.; Wang, B.; Han, J. Enthalpic Interactions of HMBA with Glycine, l-Alanine, and l-Serine in Aqueous d-Mannitol Solutions at 298.15 K. J. Chem. Eng. Data 2015, 60 (3), 845-855.
- Goel, M.; Marsh, E. N. G.; Chen, Z.; Abbott, N. L. Comparison of the influence of humidity and d-mannitol on the organization of tetraethylene glycol-terminated self-assembled monolayers and immobilized antimicrobial peptides. Langmuir 2014, 30 (24), 7143-7151.