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2-Oxazolidinone, 99%, Thermo Scientific Chemicals
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Catalog number A14543.14
also known as A14543-14
Price (USD)/ Each
45.70
-
Quantity:
25 g
Price (USD)/ Each
45.70
2-Oxazolidinone, 99%, Thermo Scientific Chemicals
Catalog numberA14543.14
Price (USD)/ Each
45.70
-
Chemical Identifiers
CAS497-25-6
IUPAC Name1,3-oxazolidin-2-one
Molecular FormulaC3H5NO2
InChI KeyIZXIZTKNFFYFOF-UHFFFAOYSA-N
SMILESO=C1NCCO1
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White
FormCrystals or powder or crystalline powder
Assay (Silylated GC)≥98.5%
Identification (FTIR)Conforms
2-Oxazolidinone is used as antimicrobials, in organisms it act as a protein synthesis inhibitors, targeting an early step involving the binding of N-formylmethionyl-tRNA to the ribosome. They are used for chiral synthesis. It has been used as an ethanolamine equivalent, also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Oxazolidinone is used as antimicrobials, in organisms it act as a protein synthesis inhibitors, targeting an early step involving the binding of N-formylmethionyl-tRNA to the ribosome. They are used for chiral synthesis. It has been used as an ethanolamine equivalent, also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives.
Solubility
Soluble in water.
Notes
Store in cool, dry conditions in a well sealed container. Store away from oxidizing agents.
2-Oxazolidinone is used as antimicrobials, in organisms it act as a protein synthesis inhibitors, targeting an early step involving the binding of N-formylmethionyl-tRNA to the ribosome. They are used for chiral synthesis. It has been used as an ethanolamine equivalent, also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives.
Solubility
Soluble in water.
Notes
Store in cool, dry conditions in a well sealed container. Store away from oxidizing agents.
RUO – Research Use Only
General References:
- Hideaki Kakeya; Masayuki Morishita; Hiroyuki Koshino; Tetsu-ichiro Morita; Kimiko Kobayashi and Hiroyuki Osada. Cytoxazone: A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp. J. Org. Chem. 1999, 64 (3), 1052-1053.
- Guo-Jie Ho; David J. Mathre. Lithium-Initiated Imide Formation. A Simple Method for N-Acylation of 2-Oxazolidinones and Bornane-2,10-Sultam. J. Org. Chem. 1995, 60 (7), 2271-2273.
- Has been used as an ethanolamine equivalent, e.g. in reaction with succinic anhydride to give 1-(2-hydroxyethyl)succinimide: Tetrahedron, 44, 261 (1988). Also behaves as an aziridine equivalent as in the conversion of thiophenols or amines to their aminoethyl derivatives: J. Org. Chem., 57, 6257 (1992).