Thermo Scientific Chemicals

Di-tert-butyl dicarbonate, 97+%, Thermo Scientific Chemicals

Catalog number: A14708.22
100 g, Each
Thermo Scientific Chemicals

Di-tert-butyl dicarbonate, 97+%, Thermo Scientific Chemicals

Catalog number: A14708.22
100 g, Each
Quantity
Catalog number: A14708.22
Price (EUR)
Quantity
-

Chemical Identifiers

CAS
24424-99-5
IUPAC Name
di-tert-butyl dicarbonate
Molecular Formula
C10H18O5
InChI Key
DYHSDKLCOJIUFX-UHFFFAOYSA-N
SMILES
CC(C)(C)OC(=O)OC(=O)OC(C)(C)C
Appearance (Color)
Clear colorless or white to pale yellow
Form
Crystals or powder or crystalline powder or fused/lumpy solid or liquid as melt
Assay from Supplier's CofA
≥97.0%

Description

Reagent for the introduction of the Boc protecting group.Di-tert-butyl dicarbonate is a reagent used for the introduction of BOC protecting group. It plays an important role in the preparation of 6-acetyl-1,2,3,4-tetrahydropyridine by reacting with 2-piperidone. It serves as a protecting group used in solid phase peptide synthesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reagent for the introduction of the Boc protecting group.Di-tert-butyl dicarbonate is a reagent used for the introduction of BOC protecting group. It plays an important role in the preparation of 6-acetyl-1,2,3,4-tetrahydropyridine by reacting with 2-piperidone. It serves as a protecting group used in solid phase peptide synthesis.

Solubility
Miscible with decalin, toluene, carbon tetrachloride, tetrahydrofuran, dioxane, alcohols, acetone, acetonitrile and dimethylformamide. Immiscible with water.

Notes
Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Moisture and light sensitive. Incompatible with oxidizing agents, reducing agents, bases and acids.
RUO – Research Use Only

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    Safety and Handling


    Classification of the substance or mixture
    CLP classification - Regulation(EC) No 1272/2008
    Flammable solids
    Category 2
    Acute Inhalation Toxicity - Vapors
    Category 1
    Skin Corrosion/Irritation
    Category 2
    Serious Eye Damage/Eye Irritation
    Category 1
    Skin Sensitization
    Category 1
    Specific target organ toxicity - (single exposure)
    Category 3
    Label Elements
    Signal Word

    Danger

    Hazard Statements

    H315 - Causes skin irritation

    H317 - May cause an allergic skin reaction

    H318 - Causes serious eye damage

    H330 - Fatal if inhaled

    H335 - May cause respiratory irritation

    Physical Hazards

    H228 - Flammable solid

    EU Specific Hazard Statements

    May form combustible dust concentrations in air

    Precautionary Statements

    P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking

    P280 - Wear protective gloves/protective clothing/eye protection/face protection

    P302 + P352 - IF ON SKIN: Wash with plenty of soap and water

    P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing

    P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing

    P310 - Immediately call a POISON CENTER or doctor/physician

    P332 + P313 - If skin irritation occurs: Get medical advice/attention