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2-Picolinic acid, 99%, Thermo Scientific Chemicals
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Catalog number A14749.22
also known as A14749-22
Price (USD)/ Each
50.65
Online exclusive
56.50 Save 5.85 (10%)
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Quantity:
100 g
Price (USD)/ Each
50.65
Online exclusive
56.50 Save 5.85 (10%)
2-Picolinic acid, 99%, Thermo Scientific Chemicals
Catalog numberA14749.22
Price (USD)/ Each
50.65
Online exclusive
56.50 Save 5.85 (10%)
-
Chemical Identifiers
CAS98-98-6
IUPAC Namepyridine-2-carboxylic acid
Molecular FormulaC6H5NO2
InChI KeySIOXPEMLGUPBBT-UHFFFAOYSA-N
SMILESOC(=O)C1=CC=CC=N1
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Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder
Melting Point (clear melt)133-140?C
Assay (Aqueous acid-base Titration)≥98.5% to ≤101.5%
Appearance (Color)White to pale cream
Assay (HPLC)≥98.5%
2-Picolinic acid is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Picolinic acid is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.
Solubility
Soluble in water. Also soluble in glacial acetic acid, ethanol and methanol. Insoluble in chloroform.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents, reducing agents and bases.
2-Picolinic acid is used as a chelate for alkaline earth metals. Used to prepare picolinato ligated transition metal complexes. In synthetic organic chemistry, has been used as a substrate in the Mitsunobu reaction and in the Hammick reaction.
Solubility
Soluble in water. Also soluble in glacial acetic acid, ethanol and methanol. Insoluble in chloroform.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents, reducing agents and bases.
RUO – Research Use Only
General References:
- Hong Zhao; Yuzhong Zhang; Zhuobin Yuan. Electrochemical determination of dopamine using a poly(2-picolinicacid) modified glassy carbon electrode. Analyst. 2001, 126, (3),358-360
- Xinjian Li; Dapeng Zou; Faqiang Leng; Chunxia Sun; Jingya Li; Yangjie Wu; Yusheng Wu. Arylation of 2-substituted pyridines via Pd-catalyzed decarboxylative cross-coupling reactions of 2-picolinic acid. Chemical Communications. 2013, 49, (3),312-314
- Has been found to accelerate significantly oxidations with chromic acid: J. Am. Chem. Soc., 98, 1026 (1976).
- Amino groups can be protected, by DCC coupling, as picolinamides, which can be cleaved with acidic Cu(OAc)2: Synth. Commun., 383 (1972).