2-Chlorobenzoyl chloride, is used in organic synthesis. It is used as a pharmaceutical intermediate for eg as an intermediate of clotrimazolc, preparation of p-chlorobenzoic acid and production of trichloro-acaricide.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Chlorobenzoyl chloride, is used in organic synthesis. It is used as a pharmaceutical intermediate for eg as an intermediate of clotrimazolc, preparation of p-chlorobenzoic acid and production of trichloro-acaricide.
Solubility
Soluble in acetone, ether, and alcohol. Solubility in water it decomposes.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Stable under recommended storage conditions. Keep away from strong bases, alcohols, oxidizing agents.
RUO – Research Use Only
General References:
- Y Zhang.; T Wei.; L Wang. Phase-transfer-catalyzed synthesis of N-aryl-N'-(2-chlorobenzoyl)-thiourea derivatives. Synthetic communications. 1997, 27 (5), 751-756.
- PC Reeves. Carboxylation of aromatic compounds: ferrocenecarboxylic acid. Organic Syntheses. 1977, 1 (5), 51-56.
- Can be used to introduce a carboxyl group into an aromatic ring by Friedel-Crafts acylation, followed by cleavage of the resulting ketone with KO-t-Bu. With this aryl group, cleavage occurs in only one of the two possible senses. For an example, (ferrocenecarboxylic acid), see: Org. Synth. Coll., 6, 625 (1988).