Methylenediphosphonic acid is used as a radioactive imaging agent, which is primarily used in skeletal scintigraphy. Due to its absorption by a variety of tumors, it is useful for the detection of neoplasms.
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Applications
Methylenediphosphonic acid is used as a radioactive imaging agent, which is primarily used in skeletal scintigraphy. Due to its absorption by a variety of tumors, it is useful for the detection of neoplasms.
Solubility
Soluble in water, dimethylsulfoxide and methanol. Slightly soluble in anhydrous ethanol. Insoluble in methylene chloride.
Notes
Store in a cool place. Incompatible with strong bases.
RUO – Research Use Only
Used as an analogue of inorganic pyrophosphate for preparation of analogues of natural di- and tri-phosphates. See, e.g.: J. Org. Chem., 44, 3997 (1979). Review: Chem. Rev., 77, 872 (1977).
The Tc complex is used in bone scintigraphy.
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Koroidov, S.; Anderlund, M. F.; Styring, S.; Thapper, A.; Messinger, J. First turnover analysis of water-oxidation catalyzed by Co-oxide nanoparticles. Energy Environ. Sci. 2015, 8 (8), 2492-2503.