1-Bromoadamantane is an important intermediate, used in synthesizing medicines and new materials etc.
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Applications
1-Bromoadamantane is an important intermediate, used in synthesizing medicines and new materials etc.
Solubility
It is soluble in organic solvents and insoluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Moisture sensitive. Keep away from Strong oxidizing agents.
RUO – Research Use Only
General References:
- SL Regen .; JJ Besse .; J McLick. Solid-phase cosolvents. Triphase catalytic hydrolysis of 1-bromoadamantane. Journal of the American Chemical. 1979 101, (1), 116-120.
- SL Regen.; L Dulak. Solid-phase cosolvents. Journal of the American Chemical society. 197799, (2), 623-625.
- Reduction with Tri-n-butyl tin hydride, A13298, generates the 1-adamantyl radical which, e.g. adds to Michael acceptors in good yield: J. Org. Chem., 53, 1285 (1988).
- With activated Ca metal (prepared from CaBr2 and Li biphenylide), forms an organocalcium reagent which reacts with ketones to give tertiary alcohols; the preparation and reactivity of these intermediates is discussed: Org. Synth. Coll., 9, 9 (1998).
- Undergoes Heck-type coupling with styrenes and arenes, catalyzed by Pd on carbon: Synthesis, 148 (1998).