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(Iodomethyl)trimethylsilane, 99%, Thermo Scientific Chemicals
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Catalog number A15120.09
also known as A15120-09
Price (USD)/ Each
92.65
Online exclusive
103.00 Save 10.35 (10%)
-
Quantity:
10 g
Price (USD)/ Each
92.65
Online exclusive
103.00 Save 10.35 (10%)
(Iodomethyl)trimethylsilane, 99%, Thermo Scientific Chemicals
Catalog numberA15120.09
Price (USD)/ Each
92.65
Online exclusive
103.00 Save 10.35 (10%)
-
Chemical Identifiers
CAS4206-67-1
Specifications
Specification Sheet
Specification SheetFormLiquid
Appearance (Color)Clear colorless to pale yellow
Assay (GC)≥98.5%
Identification (FTIR)Conforms
Refractive Index1.4900-1.4930 @ 20?C
(Iodomethyl)trimethylsilane is used for the N-alkylation of amides, in a reaction sequence to prepare unstabilized ylides for [2+3]-cycloadditions. It can react with acetoacetic acid ethyl ester to get 3-trimethylsilanyl-proπonic acid ethyl ester.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
(Iodomethyl)trimethylsilane is used for the N-alkylation of amides, in a reaction sequence to prepare unstabilized ylides for [2+3]-cycloadditions. It can react with acetoacetic acid ethyl ester to get 3-trimethylsilanyl-proπonic acid ethyl ester.
Solubility
Difficult to mix.
Notes
Light Sensitive. Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
(Iodomethyl)trimethylsilane is used for the N-alkylation of amides, in a reaction sequence to prepare unstabilized ylides for [2+3]-cycloadditions. It can react with acetoacetic acid ethyl ester to get 3-trimethylsilanyl-proπonic acid ethyl ester.
Solubility
Difficult to mix.
Notes
Light Sensitive. Store in cool, dry conditions in well sealed containers. Keep container tightly closed.
RUO – Research Use Only
General References:
- Motoo Tori.; Chiho Makino.; Kenji Hisazumi.; Masakazu Sono.; Katsuyuki Nakashima. Synthesis of a homochiral ketone having a pinguisane skeleton using phenylethylamine as a chiral auxiliary: a formal total synthesis of deoxopinguisone. Tetrahedron: Asymmetry. 2001, 12, (2), 301-307.
- Dale L. Boger.; Louis R. Cerbone.; Daniel Yohannes. Oxidative coupling of methyl 6-hydroxyindole-2-carboxylate with primary amines. Preparation of 2-substituted methyl pyrrolo[2,3-e]benzoxazole-5-carboxylates. J. Org. Chem. 1988, 53, (21), 5163-5166.