Ethylenediaminetetraacetic acid disodium salt dihydrate is used as a chelator of divalent cations. It inhibits enzymes such as metalloproteases that require divalent cations for activity. It is also used in chelation therapy. It acts as a sequestering agent in shampoos, cleaners and other personal care products and serves as an anticoagulant for blood samples.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Ethylenediaminetetraacetic acid disodium salt dihydrate is used as a chelator of divalent cations. It inhibits enzymes such as metalloproteases that require divalent cations for activity. It is also used in chelation therapy. It acts as a sequestering agent in shampoos, cleaners and other personal care products and serves as an anticoagulant for blood samples.
Solubility
Soluble in water.
Notes
Hygroscopic.Incompatible with strong oxidizing agents, strong bases, metals and copper.
RUO – Research Use Only
General References:
- Hexadentate chelating ligand for di- and trivalent cations.
- Lebeau, D.; Reiller, P. E.; Lamouroux, C. Direct analysis of ethylenediaminetetraacetic acid (EDTA) on concrete by reactive-desorption electrospray ionization mass spectrometry. Talanta 2015, 132, 877-883.
- Meszaros, A.; Fekete, J. Determination of Ethylenediaminetetraacetic Acid from Swine Organs, Feces, Urine, and Plasma by Liquid Chromatography Tandem Mass Spectrometry. Food. Anal .Methods. 2015, 8 (3), 678-684.
- Tirler, A. O.; Hofer, T. S. A Comparative Study of [CaEDTA]2- and [MgEDTA]2-: Structural and Dynamical Insights from Quantum Mechanical Charge Field Molecular Dynamics. J. Phys. Chem. B 2015, 119 (27), 8613-8622.