Pamoic acid is used in preparation of repository derivatives of medicinal agents, used in pharmacology to increase the solubility of a drug in water.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Pamoic acid is used in preparation of repository derivatives of medicinal agents, used in pharmacology to increase the solubility of a drug in water.
Solubility
Soluble in nitrobenzene, pyridine
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
General References:
- Kristof Prinsen.; Junjie Li.; Hubert Vanbilloen.; Peter Vermaelen.; Ellen Devos.; Luc Mortelmans.; Guy Bormans.; Yicheng Ni.; Alfons Verbruggen. Development and evaluation of a 68Ga labeled pamoic acid derivative for in vivo visualization of necrosis using positron emission tomography. Bioorganic & Medicinal Chemistry. 2010, 18, (14), 5274-5281.
- Miao Du.; Zhi-Hui Zhang.; Wei Guo.; Xiao-Juan Fu. Multi-Component Hydrogen-Bonding Assembly of a Pharmaceutical Agent Pamoic Acid with Piperazine or 4,4'-Bipyridyl: A Channel Hydrated Salt with Multiple-Helical Motifs vs a Bimolecular Cocrystal. Cryst. Growth Des. 2009, 9, (4), 1655-1657.