It was used as internal standard in determination of 4-nitrophenol and 3-methyl-4-nitrophenol in human urine by liquid chromatography combined with tandem mass spectrometry. ,6-Dimethyl-4-nitrophenol was used to study the disposition requirement for binding of p-nitrophenol and sodium p-nitrophenolate like substrates with cyclohexaamylaose.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It was used as internal standard in determination of 4-nitrophenol and 3-methyl-4-nitrophenol in human urine by liquid chromatography combined with tandem mass spectrometry. ,6-Dimethyl-4-nitrophenol was used to study the disposition requirement for binding of p-nitrophenol and sodium p-nitrophenolate like substrates with cyclohexaamylaose.
Solubility
Insoluble in water.
Notes
Store in cool, dry conditions in a well sealed container. Store away from oxidizing agents.
RUO – Research Use Only
Juan V Sancho; Oscar J Pozo; Francisco J López; Félix Hernández. Different quantitation approaches for xenobiotics in human urine samples by liquid chromatography/electrospray tandem mass spectrometry. Rapid Communications in Mass Spectrometry. 2002, 16 (7), 639-645.
Raymond J. Bergeron; Michael Almy Channing; George J. Gibeily; David M. Pillor. Disposition requirements for binding in aqueous solution of polar substrates in the cyclohexaamylose cavity. J. Am. Chem. Soc. 2012, 99 (15), 5146-5151.