4-Fluorobenzylamine is used as a potassium channel blocking agent. It is used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands. It reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate2. It is an important building block for the synthesis of 18F-labeled compounds.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Fluorobenzylamine is used as a potassium channel blocking agent. It is used in the synthesis of new tris-iron(III) chelates of 3-hydroxy-4-pyridinone ligands. It reacts with the α- and γ-carboxyl groups of folic acid to yield 18F-labeled folate2. It is an important building block for the synthesis of 18F-labeled compounds.
Solubility
Soluble in water.
Notes
Air sensitive. Store under inert gas. Incompatible with oxidizing agent, air, carbon dioxide.
RUO – Research Use Only
Walkiria Schlindwein; Emma Waltham; John Burgess; Norman Binsted; Ana Nunes; Andreia Leite; Maria Rangel. New lipophilic 3-hydroxy-4-pyridinonate iron(III) complexes: synthesis and EXAFS structural characterisation. Dalton Transactions. 2006, 10, 1313-1321.
Jenilee Way; Frank Wuest. Fully automated synthesis of 4-[18F]fluorobenzylamine based on borohydrideiCl2reduction. Nuclear Medicine and Biology. 2013, 40 (3), 411-416.