D-(-)-2-Phenylglycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Used to prepare semisynthetic antibiotics amoxicillin.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
D-(-)-2-Phenylglycine is an inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors. Used to prepare semisynthetic antibiotics amoxicillin.
Solubility
Soluble in water (0.3g/100mL) and aqueous acid.
Notes
Store at room temperature. Store in cool dry place in tightly closed container. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Norbert Engel; Dr. Börries Kübel; and Prof. Dr. Wolfgang Steglich. C[BOND]C Linkage of Carboxylic Acids with Allyl Alcohols Using 2-Phenylglycine as Vehicle. Angewandte Chemie International Edition. 1977, 16 (6), 394-396.
- Philippe Remuzon; Maxime Soumeillant; Christian Dussy; Daniel Bouzard. Synthesis of chiral α-substituted N-[((2S)-2-hydroxy-2-phenyl)-ethyl]-2-phenylglycine derivatives by diastereocontrolled alkylation of (6 R)-2,3,5,6-tetrahydro-3,6-diaryl-N-[(2'R)-(2'-methyl)phenyl-methyl]-4H-1,4-oxazin-2-ones. Tetrahedron. 1977, 53 (52), 17711-17726.