3-Thiophenecarboxylic acid has been used in the preparation of novel acetylene monomer, required for the synthesis of poly(2-methylbut-2-enyl thiophene-3-carboxylate) and oxazolines and oxazoles. It is also used as a lading compound for the development of a clinic useful D-amino acid inhibitor and have the potential to sever as active site proves to elucidate the structure-function relationships of D-amino acids.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3-Thiophenecarboxylic acid has been used in the preparation of novel acetylene monomer, required for the synthesis of poly(2-methylbut-2-enyl thiophene-3-carboxylate) and oxazolines and oxazoles. It is also used as a lading compound for the development of a clinic useful D-amino acid inhibitor and have the potential to sever as active site proves to elucidate the structure-function relationships of D-amino acids.
Solubility
Soluble in water at 20°C 4.3 g/L.
Notes
Store away from oxidizing agents and bases. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- D A Heerding, et al.1,4-Disubstituted imidazoles are potential antibacterial agents functioning as inhibitors of enoyl acyl carrier protein reductase (FabI).Bioorg Med Chem Lett.,2001,11(16), 2061-2065.
- Banu Koz, et al. Synthesis and characterization of polyacetylene with side-chain thiophene functionality.Int J Mol Sci.,2008,9(3), 383-393.