Homopiperazine, 98%, Thermo Scientific Chemicals
Homopiperazine, 98%, Thermo Scientific Chemicals
Thermo Scientific™

Homopiperazine, 98%, Thermo Scientific Chemicals

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Quantity:
100 g
25 g
Catalog number A15751.22
also known as A15751-22
Price (USD)/ Each
297.65
Online exclusive
330.00 
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Quantity:
100 g
Request bulk or custom format
Price (USD)/ Each
297.65
Online exclusive
330.00 
Save 32.35 (10%)
Add to cart
Homopiperazine, 98%, Thermo Scientific Chemicals
Catalog numberA15751.22
Price (USD)/ Each
297.65
Online exclusive
330.00 
Save 32.35 (10%)
-
Add to cart
Chemical Identifiers
CAS505-66-8
IUPAC Name1,4-diazepane
Molecular FormulaC5H12N2
InChI KeyFQUYSHZXSKYCSY-UHFFFAOYSA-N
SMILESC1CNCCNC1
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SpecificationsSpecification SheetSpecification Sheet
Assay (GC)≥97.5%
Water Content (Karl Fischer Titration)≤1.5%
Appearance (Color)White to yellow
FormFused solid
Melting Point36.0-42.0?C
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Homopiperazine is used to prepare 1,4-bis-(2-thiazolyl)-1,4-diazacycloheptane by reacting with 2-bromo-thiazole. It acts as an intermediate for repaglinide and fasudil hydrochloride. It is also used in the preparation of potent H3 receptor antagonists, which is used for the treatment of neurodegenerative conditions. Further, it is used in vesicant, cosmetic, emulsifier and energetic material. It acts as a corrosion inhibitor for iron. In pharmaceuticals, it is employed as antipyretic and reducing blood sugar, adiposity, calm, antipsychotic and anti-nervous.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Homopiperazine is used to prepare 1,4-bis-(2-thiazolyl)-1,4-diazacycloheptane by reacting with 2-bromo-thiazole. It acts as an intermediate for repaglinide and fasudil hydrochloride. It is also used in the preparation of potent H3 receptor antagonists, which is used for the treatment of neurodegenerative conditions. Further, it is used in vesicant, cosmetic, emulsifier and energetic material. It acts as a corrosion inhibitor for iron. In pharmaceuticals, it is employed as antipyretic and reducing blood sugar, adiposity, calm, antipsychotic and anti-nervous.

Solubility
Soluble in water.

Notes
Hygroscopic. Air sensitive. Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only

General References:

  1. Keypour, H.; Rezaeivala, M.; Mirzaei-Monsef, M.; Sayin, K.; Dilek, N.; Unver, H. Synthesis and characterization of Co(II), Ni(II), Cu(II) and Zn(II) complexes with a new homopiperazine macrocyclic Schiff base ligand. Inorg. Chim. Acta 2015, 432, 243-249.
  2. Vinodh, R.; Bhagiyalakshmi, M.; Hemalatha, P.; Ganesh, M.; Peng, M. M.; Palanichamy, M.; Cha, W. S.; Jang, H. T. Homopiperazine Grafted Mesoporous Silicas from Rice Husk Ash for CO2 Adsorption. J. Nanosci. Nanotechnol. 2014, 14 (6), 4639-4648.