Methyl 3-bromobenzoate, 98+%, Thermo Scientific Chemicals
Methyl 3-bromobenzoate, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Methyl 3-bromobenzoate, 98+%, Thermo Scientific Chemicals

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50 g
10 g
250 g
Catalog number A16174.18
also known as A16174-18
Price (USD)/ Each
229.00
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Quantity:
50 g
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Price (USD)/ Each
229.00
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Methyl 3-bromobenzoate, 98+%, Thermo Scientific Chemicals
Catalog numberA16174.18
Price (USD)/ Each
229.00
-
Add to cart
Chemical Identifiers
CAS618-89-3
IUPAC Namemethyl 3-bromobenzoate
Molecular FormulaC8H7BrO2
InChI KeyKMFJVYMFCAIRAN-UHFFFAOYSA-N
SMILESCOC(=O)C1=CC=CC(Br)=C1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White to cream
Melting Point (clear melt)28.0-35.0?C
FormFused solid
Assay (GC)≥98.0%
Methyl 3-bromobenzoate is used as a reagent in organic synthesis. It is used in the synthesis of tetrahydro dibenzazocine, which acts as an inhibitor of 17beta-hydroxysteroid dehydrogenase type 3. Further, it is used to prepare 3-tert-butylphosphanyl-benzoic acid methyl ester by reacting with tert-butyltrimethylsilylphosphine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Methyl 3-bromobenzoate is used as a reagent in organic synthesis. It is used in the synthesis of tetrahydro dibenzazocine, which acts as an inhibitor of 17beta-hydroxysteroid dehydrogenase type 3. Further, it is used to prepare 3-tert-butylphosphanyl-benzoic acid methyl ester by reacting with tert-butyltrimethylsilylphosphine.

Solubility
Slightly soluble in water.

Notes
Incompatible with strong oxidizing agents, strong acids and strong bases.
RUO – Research Use Only

General References:

  1. Semmes, J. G.; Bevans, S. L.; Mullins, C. H.; Shaughnessy, K. H. Arylation of diethyl malonate and ethyl cyanoacetate catalyzed by palladium/di-tert-butylneopentylphosphine. Tetrahedron Lett. 2015, 56 (23), 3447-3450.
  2. Peña-López, M.; Rosas-Hernández, A.; Beller, M. Progress on All Ends for Carbon-Carbon Bond Formation through Photoredox Catalysis. Angew. Chem. Int. Ed. 2015, 54 (17), 5006-5008.