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2-Aminoethyl diphenylborinate, 98%, Thermo Scientific Chemicals
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Catalog number A16606.14
Price (USD)/ Each
216.65
Online exclusive
241.00 Save 24.35 (10%)
-
Quantity:
25 g
Price (USD)/ Each
216.65
Online exclusive
241.00 Save 24.35 (10%)
2-Aminoethyl diphenylborinate, 98%, Thermo Scientific Chemicals
Catalog numberA16606.14
Price (USD)/ Each
216.65
Online exclusive
241.00 Save 24.35 (10%)
-
Chemical Identifiers
CAS524-95-8
IUPAC Name2-aminoethyl diphenylborinate
Molecular FormulaC14H16BNO
InChI KeyBLZVCIGGICSWIG-UHFFFAOYSA-N
SMILESNCCOB(C1=CC=CC=C1)C1=CC=CC=C1
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Specifications
Specification Sheet
Specification SheetMelting Point (clear melt)188.0-195.0?C
Assay (Non-aqueous acid-base Titration)≥97.5 to ≤102.5%
Appearance (Color)White to pale cream
Identification (FTIR)Conforms
FormCrystals or powder or crystalline powder
2-Aminoethyl diphenylborinate is used for the densitometric determination of flavonoids and TRP activator. It is also used to manipulate intracellular release of calcium ions and in preparation of apoptotic inducers. It serves as a reactant for preparation of apoptotic inducers and in membrane-permeable SOCE (store operated calcuym entry) inhibitor.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Aminoethyl diphenylborinate is used for the densitometric determination of flavonoids and TRP activator. It is also used to manipulate intracellular release of calcium ions and in preparation of apoptotic inducers. It serves as a reactant for preparation of apoptotic inducers and in membrane-permeable SOCE (store operated calcuym entry) inhibitor.
Solubility
Soluble in ethanol and methanol.
Notes
Incompatible with strong oxidizing agents.
2-Aminoethyl diphenylborinate is used for the densitometric determination of flavonoids and TRP activator. It is also used to manipulate intracellular release of calcium ions and in preparation of apoptotic inducers. It serves as a reactant for preparation of apoptotic inducers and in membrane-permeable SOCE (store operated calcuym entry) inhibitor.
Solubility
Soluble in ethanol and methanol.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Reagent for densitometric determination of flavonoids: J. Chromat., 351, 351 (1986); 437, 260 (1988).
- Ozaki, S.; Suzuki, A. Z.; Bauer, P. O.; Ebisui, E.; Mikoshiba, K. 2-Aminoethyl diphenylborinate (2-APB) analogues: Regulation of Ca2+ signaling. Biochem. Biophys. Res. Commun. 2013, 441 (2), 286-290.
- Hofer, A.; Kovacs, G.; Zappatini, A.; Leuenberger, M.; Hediger, M. A.; Lochner, M. Design, synthesis and pharmacological characterization of analogs of 2-aminoethyl diphenylborinate (2-APB), a known store-operated calcium channel blocker, for inhibition of TRPV6-mediated calcium transport. Bioinorg. Med. Chem. 2013, 21 (11), 3202-3213.
- Yildar, M.; Aksit, H.; Korkut, O.; Ozyigit, M. O.; Sunay, B.; Seyrek, K. Protective effect of 2-aminoethyl diphenylborinate on acute ischemia-reperfusion injury in the rat kidney. J. Surg. Res. 2014, 187 (2), 683-689.
- Mossaad, E.; Furuyam, W.; Enomoto,M.; Kawai, S.; Mikoshibaf, K.; Kawazu, S. Simultaneous Administration of 2-Aminoethyl Diphenylborinate and Chloroquine Reverses Chloroquine Resistance in Malaria Parasites. Antimicrob. Agents Chemother. 2015,59 (5), 2890-2892.
- Agatonovic-Kustrin, S.; Hettiarachchi, C. G.; Morton, D. W.; Razic, S. Analysis of phenolics in wine by high performance thin-layer chromatography with gradient elution and high resolution plate imaging. J. Pharm. Biomed. Anal. 2015, 102, 93-99.