Benzo-1,4-dioxane (2,3-dihydro-1,4-benzodioxin) is used in the synthesis of stereoisomers which were evaluated as α- and β- adrenergic antagonists
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Applications
Benzo-1,4-dioxane (2,3-dihydro-1,4-benzodioxin) is used in the synthesis of stereoisomers which were evaluated as α- and β- adrenergic antagonists
Solubility
Slightly soluble in water.
Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
General References:
- Magali Massacret.; Catherine Goux.; Paul Lhoste.; Denis Sinou. One-pot preparation of chiral 2-vinyl-1,4-benzodioxane. Tetrahedron Letters. 1994, 35, (33), 6093-6096.
- Wendel L. Nelson.; Mark L. Powell.; Donald C. Dyer. Absolute configuration of glycerol derivatives. 7. Enantiomers of 2-[[[2-(2,6-dimethoxyphenoxy)ethyl]amino]ethyl]-1,4-benzodioxane (WB-4101), a potent competitive .alpha.-adrenergic antagonist. J. Med. Chem. 1979, 22, (9), 1125-1127.