It is employed as a reactant involved in synthesis of β-1,3-dicarbonyl aldehydes via oxidation, knoevenagel condensation using a lysine catalyst, and cycloisomerization for the synthesis of trisubstituted furans. It is also a reactant for the fluorination by HF and iodosylbenzene, intramolecular Michael addition reactions and synthesis of diols. Also applied in the synthesis of diols via reduction of aromatic and aliphatic ketos esters6 and cross-coupling reactions for stereo selective synthesis of unsymmetrical 1,4-enediones.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is employed as a reactant involved in synthesis of β-1,3-dicarbonyl aldehydes via oxidation, knoevenagel condensation using a lysine catalyst, and cycloisomerization for the synthesis of trisubstituted furans. It is also a reactant for the fluorination by HF and iodosylbenzene, intramolecular Michael addition reactions and synthesis of diols. Also applied in the synthesis of diols via reduction of aromatic and aliphatic ketos esters6 and cross-coupling reactions for stereo selective synthesis of unsymmetrical 1,4-enediones.
Notes
Store away from oxidizing agents. Keep the container tightly closed in a cool, dry place.
RUO – Research Use Only
Weiping Liu.; Jinhua Liu.; Daisuke Ogawa.; Yasushi Nishihara.; Xingwei Guo.; Zhiping Li. Iron-catalyzed oxidation of tertiary amines: synthesis of β-1,3-dicarbonyl aldehydes by three-component C-C couplings.Org Lett.,2011,13(23), 6272-6275.
Tsugio Kitamura.; Satoshi Kuriki.; Mohammad Hasan Morshed.; Yuji Hori. A practical and convenient fluorination of 1,3-dicarbonyl compounds using aqueous HF in the presence of iodosylbenzene.Org Lett.2011,13(9), 2392-2394.