Glutaraldehyde, 25% aq. soln., Thermo Scientific Chemicals
Glutaraldehyde, 25% aq. soln., Thermo Scientific Chemicals
Thermo Scientific Chemicals

Glutaraldehyde, 25% aq. soln., Thermo Scientific Chemicals

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Catalog number A17876.AP
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51.65
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Quantity:
500 mL
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Price (USD)/ Each
51.65
Online exclusive
57.00 
Save 5.35 (9%)
Add to cart
Glutaraldehyde, 25% aq. soln., Thermo Scientific Chemicals
Catalog numberA17876.AP
Price (USD)/ Each
51.65
Online exclusive
57.00 
Save 5.35 (9%)
-
Add to cart
Chemical Identifiers
CAS111-30-8
IUPAC Namepentanedial
Molecular FormulaC5H8O2
InChI KeySXRSQZLOMIGNAQ-UHFFFAOYSA-N
SMILESO=CCCCC=O
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SpecificationsSpecification SheetSpecification Sheet
FormLiquid
Appearance (Color)Clear colorless to pale yellow
Assay (Aqueous acid-base Titration)23.0-27.0% (non-U.S. specification)
Assay from Suppliers CofA23.0-27.0% (U.S. specification)
CommentSpecification differs for U.S. and non-U.S. material where indicated
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Glutaraldehyde is used for cross-linking proteins and polyhydroxy materials. Also used as a fixative for tissues and as an amine-reactive homobifunctional crosslinker. It is also used in coupling reaction of biotin hydrazides to nucleic acids which is useful for conjugating fluorescent hydrazides and hydroxylamines to DNA and for stabilization ofproteins on agarose beads,activation of polystyrene and glass, for immobilization of antibodies and antigens.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Glutaraldehyde is used for cross-linking proteins and polyhydroxy materials. Also used as a fixative for tissues and as an amine-reactive homobifunctional crosslinker and as a disinfectant for medical equipment. It is also used in coupling reaction of biotin hydrazides to nucleic acids which is useful for conjugating fluorescent hydrazides and hydroxylamines to DNA and for stabilization ofproteins on agarose beads,activation of polystyrene and glass, for immobilization of antibodies and antigens. It is a disinfectant, which is rapidly effective against vegetative forms of Gram-positiveand Gram-negative bacteria.

Solubility
Miscible with water, ethanol, benzene, ether, acetone, dichloromethane, ethylacetate, isopropanol, n-hexane and toluene.

Notes
Heat and air sensitive. Incompatible with strong acids, strong bases and strong oxidizing agents.
RUO – Research Use Only

General References:

  1. For use in the Robinson synthesis of pseudopelletierine, see Acetone-1,3-dicarboxyl ic acid, A13742.
  2. Reaction with (R)-(-)-2-Phenyl glycinol, A19030, gives an intermediate for asymmetric synthesis of alkaloids: Org. Synth. Coll., 9, 176 (1998).
  3. Cho, K. L.; Hill, A. J.; Caruso, F.; Kentish, S. E. Chlorine Resistant Glutaraldehyde Crosslinked Polyelectrolyte Multilayer Membranes for Desalination. Adv. Mater. 2015, 27 (17), 2791-2796.
  4. Vikram, A.; Bomberger, J. M.; Bibby, K. J. Efflux as a Glutaraldehyde Resistance Mechanism in Pseudomonas fluorescens and Pseudomonas aeruginosa Biofilms. Antimicrob. Agents Chemother. 2015, 59 (6), 3433-3440.