CHES is zwitterionic buffer useful in pH range 8.6 to 10.0.CHES is widely utilized as a buffer which is used for investigations on pH-dependent processes in enzymology. It has been shown to have an unusually high affinity for the iodoacetate binding site of liver alcohol dehydrogenase.
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Applications
CHES is zwitterionic buffer useful in pH range 8.6 to 10.0.CHES is widely utilized as a buffer which is used for investigations on pH-dependent processes in enzymology. It has been shown to have an unusually high affinity for the iodoacetate binding site of liver alcohol dehydrogenase.
Solubility
Soluble in water.
Notes
Store in cool place. Hygroscopic. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Biological buffer, pKa = 9.3 at 20°: Biochemistry, 5, 467 (1966).
- Ferreira, C. M. H.; Pinto, I. S. S.; Soares, E. V.; Soares, H. M. V. M. (Un)suitability of the use of pH buffers in biological, biochemical and environmental studies and their interaction with metal ions - a review. RSC Adv. 2015, 5 (39), 30989-31003.
- Devi, T. S. R.; kumar, J. S.; Ramkumaar, G. R. DFT analysis on the molecular structure, vibrational and electronic spectra of 2-(cyclohexylamino)ethanesulfonic acid. Spectrochim. Acta, Part A 2015, 137, 761-777.