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4-Nitrophenyl chloroformate, 97%, Thermo Scientific Chemicals
Catalog number: A18742.22
100 g, Each
Thermo Scientific Chemicals
4-Nitrophenyl chloroformate, 97%, Thermo Scientific Chemicals
Catalog number: A18742.22
100 g, Each
Quantity
Catalog number: A18742.22
also known as A18742-22
Price (USD)
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Chemical Identifiers
CAS
7693-46-1
IUPAC Name
4-nitrophenyl carbonochloridate
Molecular Formula
C7H4ClNO4
InChI Key
NXLNNXIXOYSCMB-UHFFFAOYSA-N
SMILES
[O-][N+](=O)C1=CC=C(OC(Cl)=O)C=C1
Specifications
Specification SheetAssay (Titration ex Chloride)
≥96.0 to ≤104.0%
Melting Point (clear melt)
74.0-85.0?C
Form
Crystals or powder or crystalline powder or fused solid
Identification (FTIR)
Conforms
Appearance (Color)
White to cream to pale gray
Description
4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane.
Solubility
Soluble in acetone, chloroform, acetone, toluene and benzene.
Notes
Moisture sensitive. Store in a cool place. Incompatible with water, acids, alcohols, ammonia, amines and strong bases.
4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane.
Solubility
Soluble in acetone, chloroform, acetone, toluene and benzene.
Notes
Moisture sensitive. Store in a cool place. Incompatible with water, acids, alcohols, ammonia, amines and strong bases.
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