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(R)-(-)-2-Phenylglycinol, 98%, Thermo Scientific Chemicals
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Catalog number A19030.06
also known as A19030-06
Price (USD)/ Each
102.00
-
Quantity:
5 g
Price (USD)/ Each
102.00
(R)-(-)-2-Phenylglycinol, 98%, Thermo Scientific Chemicals
Catalog numberA19030.06
Price (USD)/ Each
102.00
-
Chemical Identifiers
CAS56613-80-0
IUPAC Name(1S)-2-hydroxy-1-phenylethan-1-aminium
Molecular FormulaC8H12NO
InChI KeyIJXJGQCXFSSHNL-MRVPVSSYSA-O
SMILES[NH3+][C@H](CO)C1=CC=CC=C1
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Specifications
Specification Sheet
Specification SheetAssay (HPLC)≥97.5%
Optical Rotation-30.5 ± 2.5? (C=1.0 in 1N HCl)
FormCrystals or powder or crystalline powder
Appearance (Color)White to cream to yellow
Melting Point (clear melt)74.0-81.0?C
Amino alcohol used to prepare a chiral imine or oxazolidine from ethyl trifluoropyruvate. These intermediates were then employed in a synthesis of both enantiomers of α-trifluoromethylproline. Chiral β-amino alcohol used as a synthetic building block.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Amino alcohol used to prepare a chiral imine or oxazolidine from ethyl trifluoropyruvate. These intermediates were then employed in a synthesis of both enantiomers of α-trifluoromethylproline. Chiral β-amino alcohol used as a synthetic building block.
Solubility
Slightly soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Amino alcohol used to prepare a chiral imine or oxazolidine from ethyl trifluoropyruvate. These intermediates were then employed in a synthesis of both enantiomers of α-trifluoromethylproline. Chiral β-amino alcohol used as a synthetic building block.
Solubility
Slightly soluble in water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
General References:
- Grégory Chaume et. al. Straightforward synthesis of (S)- and (R)-alpha-trifluoromethyl proline from chiral oxazolidines derived from ethyl trifluoropyruvate.. Organic Letters. 2006, 8 (26), 6123-6126.
- Amberley S. Anslow,; Laurence M. Harwood,; Helen Phillips,; David Watkib .Development of a chiral stabilised azomethine ylid. A chiral relay system.. Tetrahedron: Asymmetry. year of publication , 2 (3), 169-172.
- Condensation with glutaraldehyde gives a useful intermediate in asymmetric synthesis of alkaloids: Org. Synth. Coll., 9, 176 (1998):
- Starting material for the enantioselective synthesis of 2,6-disubstituted piperazines: Synthesis, 833 (1996), and for chiral ɑ-amino phosphonates: Org. Synth., 75, 19 (1997).