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Spermidine, 99%, Thermo Scientific Chemicals
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Catalog number A19096.03
also known as A19096-03
Price (USD)/ Each
39.65
Online exclusive
43.90 Save 4.25 (10%)
-
Quantity:
1 g
Price (USD)/ Each
39.65
Online exclusive
43.90 Save 4.25 (10%)
Spermidine, 99%, Thermo Scientific Chemicals
Catalog numberA19096.03
Price (USD)/ Each
39.65
Online exclusive
43.90 Save 4.25 (10%)
-
Chemical Identifiers
CAS124-20-9
Specifications
Specification Sheet
Specification SheetAssay (GC)≥98.5% (non-U.S. specification)
Appearance (Color)Clear colorless to pale yellow or white to pale cream
Assay from Suppliers CofA≥98.5% (U.S. specification : GC)
Refractive Index1.4770-1.4810 @ 20°C (non-U.S. specification)
FormLiquid as melt or solid @ <20°C
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Binds to the polyamine modulatory site of NMDA Spermidine is used in electroporation during transferring the DNA into the cell under the electrical impulse. It is also used for purification of DNA-binding proteins. It combines with calcium chloride and utilized for the precipitation of DNA onto microprojectiles for bombardment with a gene gun. It plays an important role to reduce the amount of aging in yeast, flies, worms, and human immune cells by inducing autophagy. It serves as a precursor of spermine and essential for both normal and neoplastic tissue growth.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Binds to the polyamine modulatory site of NMDA Spermidine is used in electroporation during transferring the DNA into the cell under the electrical impulse. It is also used for purification of DNA-binding proteins. It combines with calcium chloride and utilized for the precipitation of DNA onto microprojectiles for bombardment with a gene gun. It plays an important role to reduce the amount of aging in yeast, flies, worms, and human immune cells by inducing autophagy. It serves as a precursor of spermine and essential for both normal and neoplastic tissue growth.
Solubility
Miscible with water, ethanol and ether.
Notes
Hygroscopic. Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.
Binds to the polyamine modulatory site of NMDA Spermidine is used in electroporation during transferring the DNA into the cell under the electrical impulse. It is also used for purification of DNA-binding proteins. It combines with calcium chloride and utilized for the precipitation of DNA onto microprojectiles for bombardment with a gene gun. It plays an important role to reduce the amount of aging in yeast, flies, worms, and human immune cells by inducing autophagy. It serves as a precursor of spermine and essential for both normal and neoplastic tissue growth.
Solubility
Miscible with water, ethanol and ether.
Notes
Hygroscopic. Incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents.
RUO – Research Use Only
General References:
- Pietrocola, F.; Lachkar, S.; Enot, D. P.; Niso-Santano, M.; Bravo-San Pedro, J. M.; Sica, V.; Izzo, V.; Maiuri, M C.; Madeo, F.; Mariño, G.; Kroemer, G. Spermidine induces autophagy by inhibiting the acetyltransferase EP300. Cell Death Differ. 2015, 22 (3), 509-516.
- Ibarra, A. A. G.; Wrobel, K.; Escobosa, A. R. C.; Elguera, J. C. T.; Garay-Sevilla, M. E.; Wrobel, K. Determination of putrescine, cadaverine, spermidine and spermine in different chemical matrices by high performance liquid chromatography-electrospray ionization-ion trap tandem mass spectrometry (HPLC-ESI-ITMS/MS). J. Chromatogr. B 2015, 1002, 176-184.