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N,N'-Diisopropylcarbodiimide, 99%, Thermo Scientific Chemicals
Alfa Aesar N,N'-Diisopropylcarbodiimide, 99%, Quantity: 50g, Boiling Point: 145 deg.C to 148 deg.C, Molecular Weight: 126.203, Percent Purity: 99%, Beilstein: 878281, CAS: 693-13-0, ChEBI: CHEBI:53092, Density: 0.81, DOT Information: Hazard Class: 6.1; Packaging Group: I, EINECS Number: 211-743-7
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Catalog number A19292.09
also known as A19292-09
Price (USD)/ Each
36.65
Online exclusive
40.20 Save 3.55 (9%)
-
Quantity:
10 g
Price (USD)/ Each
36.65
Online exclusive
40.20 Save 3.55 (9%)
N,N'-Diisopropylcarbodiimide, 99%, Thermo Scientific Chemicals
Catalog numberA19292.09
Price (USD)/ Each
36.65
Online exclusive
40.20 Save 3.55 (9%)
-
Chemical Identifiers
CAS693-13-0
IUPAC Name(propan-2-yl)({[(propan-2-yl)imino]methylidene})amine
Molecular FormulaC7H14N2
InChI KeyBDNKZNFMNDZQMI-UHFFFAOYSA-N
SMILESCC(C)N=C=NC(C)C
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Specifications
Specification Sheet
Specification SheetFormLiquid
CommentMaterial Sourced in UK and US
Refractive Index1.4320-1.4350 @ 20?C (UK Sourced Material)
Appearance (Color)Clear colorless to yellow
Assay from Supplier's CofA≥98.5% (US Sourced Material)
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N,N'-Diisopropylcarbodiimide is used as a reagent in synthetic organic chemistry. It serves as a chemical intermediate and as a stabilizer for Sarin (chemical weapon). It is also used in the synthesis of peptide and nucleic acid. Further, it is used as an antineoplastic and involved in the treatment of malignant melanoma and sarcomas. In addition to this, it is used in the synthesis of acid anhydride, aldehyde, ketone and isocyanate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
N,N′-Diisopropylcarbodiimide is used as a reagent in synthetic organic chemistry. It serves as a chemical intermediate and as a stabilizer for Sarin (chemical weapon). It is also used in the synthesis of peptide and nucleic acid. Further, it is used as an antineoplastic and involved in the treatment of malignant melanoma and sarcomas. In addition to this, it is used in the synthesis of acid anhydride, aldehyde, ketone and isocyanate.
Solubility
Soluble in chloroform, methylene chloride, acetonitrile, dioxane, dimethylformamide andtetrahydrofuran.
Notes
Moisture sensitive. Store in a cool place Incompatible with oxidizing agents and acids.
N,N′-Diisopropylcarbodiimide is used as a reagent in synthetic organic chemistry. It serves as a chemical intermediate and as a stabilizer for Sarin (chemical weapon). It is also used in the synthesis of peptide and nucleic acid. Further, it is used as an antineoplastic and involved in the treatment of malignant melanoma and sarcomas. In addition to this, it is used in the synthesis of acid anhydride, aldehyde, ketone and isocyanate.
Solubility
Soluble in chloroform, methylene chloride, acetonitrile, dioxane, dimethylformamide andtetrahydrofuran.
Notes
Moisture sensitive. Store in a cool place Incompatible with oxidizing agents and acids.
RUO – Research Use Only
General References:
- Reagent for peptide coupling: J. Org. Chem., 44, 5000 (1979). Has the advantage over N,N'-Dicyclohexyl carbodiimide, A10973 in solid phase peptide syntheses that the urea by-product is more soluble in organic solvents and hence more readily separated from the polymer support. For peptide reagents, see Appendix 6.
- Ogawa, T.; Usuki, N.; Nakazono, K.; Koyama, Y.; Takata, T. Linear-cyclic polymer structural transformation and its reversible control using a rational rotaxane strategy. Chem. Commun. 2015, 51 (26), 5606-5609.
- Smith, J. M.; Moreno, J.; Boal, B. W.; Garg, N. K. Cascade Reactions: A Driving Force in Akuammiline Alkaloid Total Synthesis. Angew. Chem. Int. Ed. 2015, 54 (2), 400-412.