N,N-Diethylethylenediamine was used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides. It is also used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma.
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Applications
N,N-Diethylethylenediamine was used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides. It is also used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma.
Solubility
Miscible in water.
Notes
Air sensitive. Store away from oxidizing agents. Protect against electrostatic charges. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- J M Dagle, et. al. Targeted elimination of zygotic messages in Xenopus laevis embryos by modified oligonucleotides possessing terminal cationic linkages.Nucleic Acids Res.2000,28(10), 2153-2157.
- A. B. P. Lever, et al. Temperature-dependent tetragonal distortion in some thermochromic N,N-diethylethylenediamine complexes of copper(II).Inorg. Chem.,1971,10(11), 2424-2427.