Pentafluoropyridine was used in the preparation of η2-C,C coordinated pentafluoropyridine complex. It was also used in the preparation of polyfluorinated coupling products via Pd(0)-catalyzed cross-coupling reaction with diarylzinc compounds. It was also used as derivatizing reagent in the sensitive GC-MS method for determination of the four endocrine disrupting chemicals.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Pentafluoropyridine was used in the preparation of η2-C,C coordinated pentafluoropyridine complex. It was also used in the preparation of polyfluorinated coupling products via Pd(0)-catalyzed cross-coupling reaction with diarylzinc compounds. It was also used as derivatizing reagent in the sensitive GC-MS method for determination of the four endocrine disrupting chemicals.
Solubility
Not miscible or difficult to mix in water.
Notes
Store away from oxidizing agents, alkali metals and bases. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
Procacci B.; Blagg RJ.; Perutz RN, et al. Photochemical Reactions of Fluorinated Pyridines at Half-Sandwich Rhodium Complexes: Competing Pathways of Reaction.Organometallics.2014,33(1), 45-52.
Masato Ohashi, et al. Palladium-catalyzed coupling reaction of perfluoroarenes with diarylzinc compounds.Chemistry.2014,20(7), 2040-2048.
Protection of alcohols has been effected under phase-transfer conditions to give preferentially the 4-alkoxy-derivatives which can be cleaved with sodium methoxide in DMF: J. Chem. Soc., Chem. Commun., 125 (1984).