2,4,6-Trihydroxybenzaldehyde is used in the preparation of 2-methyl-phloroglucinol by hydrogenation using 5% palladium/carbon. It acts as a reactant for the synthesis of biologically active molecules such as 2,4,6-trichlorophenyl hydrazones. It is also used as a xanthine oxidase inhibitor.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2,4,6-Trihydroxybenzaldehyde is used in the preparation of 2-methyl-phloroglucinol by hydrogenation using 5% palladium/carbon. It acts as a reactant for the synthesis of biologically active molecules such as 2,4,6-trichlorophenyl hydrazones. It is also used as a xanthine oxidase inhibitor.
Solubility
Soluble in water.
Notes
Air sensitive. Incompatible with oxidizing agents and strong bases.
RUO – Research Use Only
General References:
- Ayers, S.; Shi, Z.; Marshall, J.; Fenster, M.; Huang, Y.; Pathirana, C. An unexpected product from the attempted acetal formation of 2,4,6-trihydroxybenzaldehyde. Tetrahedron Lett. 2015, 56 (36), 5132-5134.
- Suthar, S. K.; Aggarwal, V.; Chauhan, M.; Sharma, A.; Bansal, S.; Sharma, M. Molecular docking and biological evaluation of hydroxy-substituted (Z)-3-benzylideneindolin-2-one chalcones for the lead identification as tyrosinase inhibitors. Med. Chem. Res. 2015, 24 (3), 1331-1341.