Thermo Scientific Chemicals

Indomethacin, 98%, Thermo Scientific Chemicals

Catalog number: A19910.06
5 g, Each
Thermo Scientific Chemicals

Indomethacin, 98%, Thermo Scientific Chemicals

Catalog number: A19910.06
5 g, Each
Quantity
Catalog number: A19910.06
also known as A19910-06
Price (USD)
Quantity
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Chemical Identifiers

CAS
53-86-1
IUPAC Name
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl]acetic acid
Molecular Formula
C19H16ClNO4
InChI Key
CGIGDMFJXJATDK-UHFFFAOYSA-N
SMILES
COC1=CC=C2N(C(=O)C3=CC=C(Cl)C=C3)C(C)=C(CC(O)=O)C2=C1
Assay (Aqueous acid-base Titration)
≥97.5 to ≤102.5%
Melting Point (clear melt)
156.0-163.0?C
Form
Powder
Appearance (Color)
White to pale cream
Assay (HPLC)
≥97.5%

Description

It is a non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It finds its application as gout suppressant, non-steroidal anti-inflammatory drug and analgesic. It also plays many biological roles. Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.

Notes
Store away from oxidizing agents, strong bases and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

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