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DDM/CHS Solution (10:1)
DDM/CHS Solution (10:1)
Thermo Fisher Scientific™

DDM/CHS Solution (10:1)

Thermo Scientific DDM/CHS Solution (10:1) is a ready-to-use solution for solubilization of membrane proteins while maintaining structural integrity and activity.TheRead more
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Catalog NumberQuantity
A5094210 x 1 mL
Catalog number A50942
Price (USD)
200.60
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Online exclusive
Ends: 15-Aug-2025
236.00
Save 35.40 (15%)
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Quantity:
10 x 1 mL
Price (USD)
200.60
Special offer
Online exclusive
Ends: 15-Aug-2025
236.00
Save 35.40 (15%)
Each
Add to cart
Thermo Scientific DDM/CHS Solution (10:1) is a ready-to-use solution for solubilization of membrane proteins while maintaining structural integrity and activity.

The stable pre-formulated solution contains a mixture of dodecyl-β-D-maltoside (DDM) (100 mg/mL) and cholesteryl hemisuccinate (CHS) (10 mg/mL) in deionized water with final concentrations of 10% and 1%, respectively. Typical working concentrations are 1% DDM/0.1% CHS for protein extraction and 0.1% DDM/0.01% CHS for protein purification.

Features of DDM/CHS Solution include:
• Ready-to-use liquid formulation
• Mixture of nonionic detergent, DDM, with dual hydrophobic/hydrophilic properties and anionic detergent, CHS, that aids in the stabilization of large unilamellar vesicles
• DDM/CHS micelles aid in solubilization of membrane proteins while preserving structure and function
• Suitable for protein solubilization and stabilization for single particle cryo-EM analysis

Properties of DDM:
Molecular formula: C24H46O11
Molecular weight: 510.6 g
Detergent class: nonionic
Micelle molecular weight: 50,000 g
Critical micelle concentration (CMC): 0.17 mM (0.009% w/v) in water; 0.12 mM (0.006% w/v) in 0.2 M NaCl

Properties of CHS:
Molecular formula: C31H50O4 · C4H11NO3
Molecular weight: 607.9
Detergent: ionizable anionic
Function: stabilizes large unilamellar vesicles

WARNING: Cancer – www.P65Warnings.ca.gov
Specifications
Quantity10 x 1 mL
FormLiquid
Unit SizeEach

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