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Alomone Labs, LTD
ZnT4 (SLC30A4) Polyclonal Antibody
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Application
FIGURE: 1 / 4
ZnT4 (SLC30A4) Antibody (AZT-014-50UL) in IHC (F)
Expression of ZnT4 in mouse hypothalamus. Immunohistochemical staining of perfusion-fixed frozen mouse brain sections using Anti-ZnT4 (SLC30A4) Antibody (#AZT-014) (1:200), followed by goat anti-rabbit-AlexaFluor-488. A. ZnT4 immunoreactivity (green) appears in neuron outlines (arrows). B. Pre-incubation of the antibody with ZnT4 (SLC30A4) Blocking Peptide (BLP-ZT014), suppressed staining. Cell nuclei are s... View More
Product Details
AZT-014-50UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide DEVSDEGLSRFNKLR, corresponding to amino acid residues 33-47 of rat SLC30A4. Intracellular, N-terminus.
Conjugate
Unconjugated
Form
Lyophilized
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4, with 1% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Immunogen sequence: DEVSDEGLSRFNKLR
Reconstitution: 25 uL, 50 uL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
Target Information
Zinc is the second most abundant trace metal in the human body. It is an essential element, serving both a structural role, as in the formation of zinc fingers in DNA-binding proteins, and a catalytic role in metalloenzymes, such as pancreatic carboxypeptidases (e.g., MIM 114852), alkaline phosphatases (e.g., MIM 171760), various dehydrogenases, and superoxide dismutases (e.g., MIM 147450). SLC30A4, or ZNT4, belongs to the ZNT family of zinc transporters. ZNTs are involved in transporting zinc out of the cytoplasm and have similar structures, consisting of 6 transmembrane domains and a histidine-rich cytoplasmic loop (Huang and Gitschier, 1997).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Dri 27 protein; Dri 27/ZnT4 protein; Lethal milk protein; Probable proton-coupled zinc antiporter SLC30A4; solute carrier family 30 (zinc transporter), member 4; solute carrier family 30 (zinc transporter), member 4; zinc transporter 4; Solute carrier family 30 member 4; Zinc transporter 4; ZnT-4
Gene Aliases: Lm; SLC30A4; znT-4; ZNT4
UniProt ID: (Human) O14863, (Rat) O55174, (Mouse) O35149
Entrez Gene ID: (Human) 7782, (Rat) 64469, (Mouse) 22785
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