3-Cyano-6-methyl-2-pyridone, 98%, Thermo Scientific Chemicals
3-Cyano-6-methyl-2-pyridone, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

3-Cyano-6-methyl-2-pyridone, 98%, Thermo Scientific Chemicals

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50 g
10 g
250 g
Catalog number B20188.18
also known as B20188-18
Price (USD)/ Each
241.00
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Quantity:
50 g
Request bulk or custom format
Price (USD)/ Each
241.00
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3-Cyano-6-methyl-2-pyridone, 98%, Thermo Scientific Chemicals
Catalog numberB20188.18
Price (USD)/ Each
241.00
-
Add to cart
Chemical Identifiers
CAS4241-27-4
SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Pale cream to cream
FormPowder
Assay (Silylated GC)≥97.5%
3-Cyano-6-methyl-2(1H)-pyridinone is a reactant used in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. 3-It has also been used in the preparation of the N3-pyridyl thiamine, a potent in vitro thiamine antagonist.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Cyano-6-methyl-2(1H)-pyridinone is a reactant used in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. 3-It has also been used in the preparation of the N3′-pyridyl thiamine, a potent in vitro thiamine antagonist.

Solubility
Soluble in water at 20°C, 2.38 g/L.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

General References:

  1. Allen A. Thomas, et al. Synthesis, in vitro and in vivo activity of thiamine antagonist transketolase inhibitors.Bioorg Med Chem Lett.2008,18(6), 2206-2210.
  2. Munakata M, et al. Construction of three-dimensional supramolecular coordination copper (I) compounds with channel structures hosting a variety of anions by changing the hydrogen-bonding mode and distances.J. Am. Chem. Soc.1996,118(13), 3117-24.