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2-Mercapto-5-methoxybenzimidazole, 99%, Thermo Scientific Chemicals
Catalog number: B20570.14
25 g, Each
Thermo Scientific Chemicals
2-Mercapto-5-methoxybenzimidazole, 99%, Thermo Scientific Chemicals
Catalog number: B20570.14
25 g, Each
Quantity
Catalog number: B20570.14
also known as B20570-14
Price (USD)
99.50
Each
Quantity
-
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Chemical Identifiers
CAS
37052-78-1
IUPAC Name
5-methoxy-2,3-dihydro-1H-1,3-benzodiazole-2-thione
Molecular Formula
C8H8N2OS
InChI Key
KOFBRZWVWJCLGM-UHFFFAOYSA-N
SMILES
COC1=CC=C2NC(=S)NC2=C1
Specifications
Specification SheetForm
Powder
Melting Point (clear melt)
255.0-261.0?C
Appearance (Color)
Pale cream to cream
Assay (HPLC)
≥98.5%
Description
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.
Solubility
Soluble in dimethyl sulfoxide. Slightly soluble in methanol. Insoluble in water.
Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents, acids, bases and reducing agents.
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.
Solubility
Soluble in dimethyl sulfoxide. Slightly soluble in methanol. Insoluble in water.
Notes
Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents, acids, bases and reducing agents.
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