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Ethyl isonipecotate, 98%, Thermo Scientific Chemicals
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Catalog number B20601.22
also known as B20601-22
Price (USD)/ Each
113.65
Online exclusive
126.00 Save 12.35 (10%)
-
Quantity:
100 g
Price (USD)/ Each
113.65
Online exclusive
126.00 Save 12.35 (10%)
Ethyl isonipecotate, 98%, Thermo Scientific Chemicals
Catalog numberB20601.22
Price (USD)/ Each
113.65
Online exclusive
126.00 Save 12.35 (10%)
-
Chemical Identifiers
CAS1126-09-6
Specifications
Specification Sheet
Specification SheetFormLiquid
Refractive Index1.4580-1.4620 @ 20?C
Appearance (Color)Clear colorless to pale yellow
Assay (GC)≥97.5%
It is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Fully miscible with water.
Notes
Store at room temperature. Incompatible with strong oxidizing agents.
Fully miscible with water.
Notes
Store at room temperature. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Samantha J. Barry.; Richard M. Carr.; Stephen J. Lane.; William J. Leavens.; Soraya Monté.; Ian Waterhouse. Derivatisation for liquid chromatography/electrospray mass spectrometry: synthesis of pyridinium compounds and their amine and carboxylic acid derivatives.rapid communications in mass spectroscopy. 2003 , 17 (6),603-620 .
- Stephen A. Kolodziej.; Susan L. Hockerman.; Gary A. DeCrescenzo.; Joseph J. McDonald.; Debbie A. Mischke.; Grace E. Munie.; Theresa R. Fletcher.; Nathan Stehle.; Craig Swearingen.; Daniel P. Becker. MMP-13 selective isonipecotamide α-sulfone hydroxamates.Bioorg. Med. Chem. Lett. 2010, 20 (12),3561-3564 .