Sodium deoxycholate monohydrate, 98%, Thermo Scientific Chemicals

Name: Sodium deoxycholate monohydrate, 98%, Thermo Scientific Chemicals
SKU: B20759.14

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Catalog number B20759.14

also known as B20759-14

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25 g

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Chemical Identifiers

CAS145224-92-6

IUPAC Namesodium (4R)-4-[(1R,3aS,3bR,5aR,7R,9aS,9bS,11S,11aR)-7,11-dihydroxy-9a,11a-dimethyl-hexadecahydro-1H-cyclopenta[a]phenanthren-1-yl]pentanoate hydrate

Molecular FormulaC24H41NaO5

InChI KeyNDVHNZISGVSFMP-WTCAICSISA-M

SMILESO.[Na+].[H][C@@]1(CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)[C@H](C)CCC([O-])=O

Specifications

Specification Sheet

Appearance (Color)White

Optical Rotation44.0 ± 2.0° (C=2 in water, UK-sourced material)

FormPowder

Assay from Supplier's CofA≥97.5% (HPLC, US-sourced material)

Identification (FTIR)Conforms (UK-sourced material)

Sodium deoxycholate monohydrate is used as a solubilization agent for estrogen synthetase from human placental microsomes. It is also used to study the immobilization of lipoxygenase in an alginate-silicate gel matrix and to investigate the in vitro dissolution of gall stones.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Sodium deoxycholate monohydrate is used as a solubilization agent for estrogen synthetase from human placental microsomes. It is also used to study the immobilization of lipoxygenase in an alginate-silicate gel matrix and to investigate the in vitro dissolution of gall stones.

Solubility
Soluble in water.

Notes
Incompatible with oxidizing agents.

RUO – Research Use Only

General References:

Christie, M.; Torres, R. M.; Kedl, R. M.; Randolph, T. W.; Carpenter, J. F. Recombinant murine growth hormone particles are more immunogenic with intravenous than subcutaneous administration. J. Pharm. Sci. 2014, 103 (1), 128-139.
Kuhre, R. E.; Albrechtsen, N. W.; Windeløv, J. A.; Svendsen, B.; Hartmann, B.; Holst, J. J. GLP-1 amidation efficiency along the length of the intestine in mice, rats and pigs and in GLP-1 secreting cell lines. Peptides 2014, 55, 52-57.