It is a reactant for preparation of anilinopyrimidinesulfonamides as potential anticancer agents, synthesis of inhibitors of the hypoxia inducible factor pathway. It participates in the preparation of hydroxy-sulfonyl-piperidinyl butyramides as HDAC inhibitors and potential antitumors and is also involved in palladium-catalyzed desulfitative C-arylation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is a reactant for preparation of anilinopyrimidinesulfonamides as potential anticancer agents, synthesis of inhibitors of the hypoxia inducible factor pathway. It participates in the preparation of hydroxy-sulfonyl-piperidinyl butyramides as HDAC inhibitors and potential antitumors and is also involved in palladium-catalyzed desulfitative C-arylation.
Solubility
Reacts with water.
Notes
Store at room temperature. Keep away from moisture, bases and oxidizing agents.
RUO – Research Use Only
General References:
- Srinivas Reddy Dubbaka.;Pierre Vogel. Palladium-Catalyzed Suzuki-Miyaura Cross-Couplings of Sulfonyl Chlorides and Boronic Acids. Org. Lett. 2004, 6 (1),95-98 .
- Srinivas Reddy Dubbaka.; Pierre Vogel. Palladium-Catalyzed Stille Cross-Couplings of Sulfonyl Chlorides and Organostannanes.J. Am. Chem. Soc. 2003, 125 (50),15292-15293 .