Biphenyl-4-sulfonyl chloride, 97%, Thermo Scientific Chemicals
Biphenyl-4-sulfonyl chloride, 97%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Biphenyl-4-sulfonyl chloride, 97%, Thermo Scientific Chemicals

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5 g
25 g
100 g
Catalog number B21031.06
also known as B21031-06
Price (USD)/ Each
62.30
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Quantity:
5 g
Request bulk or custom format
Price (USD)/ Each
62.30
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Biphenyl-4-sulfonyl chloride, 97%, Thermo Scientific Chemicals
Catalog numberB21031.06
Price (USD)/ Each
62.30
-
Add to cart
Chemical Identifiers
CAS1623-93-4
IUPAC Name[1,1'-biphenyl]-4-sulfonyl chloride
Molecular FormulaC12H9ClO2S
InChI KeyALBQXDHCMLLQMB-UHFFFAOYSA-N
SMILESClS(=O)(=O)C1=CC=C(C=C1)C1=CC=CC=C1
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SpecificationsSpecification SheetSpecification Sheet
FormPowder
Assay (HPLC)≥96.0%
Melting Point (clear melt)111.0-120.0?C
Appearance (Color)White to cream
Identification (FTIR)Conforms
It is a reactant for preparation of anilinopyrimidinesulfonamides as potential anticancer agents, synthesis of inhibitors of the hypoxia inducible factor pathway. It participates in the preparation of hydroxy-sulfonyl-piperidinyl butyramides as HDAC inhibitors and potential antitumors and is also involved in palladium-catalyzed desulfitative C-arylation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is a reactant for preparation of anilinopyrimidinesulfonamides as potential anticancer agents, synthesis of inhibitors of the hypoxia inducible factor pathway. It participates in the preparation of hydroxy-sulfonyl-piperidinyl butyramides as HDAC inhibitors and potential antitumors and is also involved in palladium-catalyzed desulfitative C-arylation.

Solubility
Reacts with water.

Notes
Store at room temperature. Keep away from moisture, bases and oxidizing agents.
RUO – Research Use Only

General References:

  1. Srinivas Reddy Dubbaka.;Pierre Vogel. Palladium-Catalyzed Suzuki-Miyaura Cross-Couplings of Sulfonyl Chlorides and Boronic Acids. Org. Lett. 2004, 6 (1),95-98 .
  2. Srinivas Reddy Dubbaka.; Pierre Vogel. Palladium-Catalyzed Stille Cross-Couplings of Sulfonyl Chlorides and Organostannanes.J. Am. Chem. Soc. 2003, 125 (50),15292-15293 .