It is used in the synthesis and antihypertensive activity of 4'-substituted spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-ones.
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Applications
It is used in the synthesis and antihypertensive activity of 4′-substituted spiro[4H-3,1-benzoxazine-4,4′-piperidin]-2(1H)-ones.
Solubility
Insoluble in water. Solubility in methanol is almost transparent. Soluble in chloroform and ethyl acetate.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- Robin D. Clark, et al. Synthesis and antihypertensive activity of 4'-substituted spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-ones.J. Med. Chem.,198326(5), 657-661.
- Zhang-Lin Zhou, et al. 4-Hydroxy-1-[2-(4-hydroxyphenoxy)ethyl]-4-(4-methylbenzyl)piperidine: A Novel, Potent, and Selective NR1/2B NMDA Receptor Antagonist.J. Med. Chem.,1999,42(15), 2993-3000.