Tetrabutylammonium Fluoride is a reactant used for the synthesis of multiple compounds, including conjugated dienoic acid esters, oligoribonucleotides with phosphonate-modified linkages, and triple monoamine reuptake inhibitors, among others. It has proven useful in studying cancer, diabetes, and neurochemistry.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Tetrabutylammonium Fluoride is a reactant used for the synthesis of multiple compounds, including conjugated dienoic acid esters, oligoribonucleotides with phosphonate-modified linkages, and triple monoamine reuptake inhibitors, among others. It has proven useful in studying cancer, diabetes, and neurochemistry.
Solubility
Insoluble in water.
Notes
Hygroscopic. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions.Keep away from strong oxidizing agents,
RUO – Research Use Only
GVM Sharma.; VG Reddy.; AS Chander. Tetra-n-butylammonium fluoride: an efficient base for aza-Michael addition—synthesis of glycosyl β-amino acid esters. Tetrahedron: Asymmetry. 200213 (1), 21-24.
AH Narten.; S Lindenbaum. Diffraction Pattern and Structure of the System Tetra-n-butylammonium Fluoride-Water at 25°C. The Journal of Chemical Physics. 196951 (1), 1108-1110.