Thermo Scientific Chemicals

3-Quinuclidinol, 98+%, Thermo Scientific Chemicals

Catalog number: B21503.06
5 g, Each
Thermo Scientific Chemicals

3-Quinuclidinol, 98+%, Thermo Scientific Chemicals

Catalog number: B21503.06
5 g, Each
Quantity
Catalog number: B21503.06
Price (USD)
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Chemical Identifiers

CAS
1619-34-7
IUPAC Name
1-azabicyclo[2.2.2]octan-3-ol
Molecular Formula
C7H13NO
InChI Key
IVLICPVPXWEGCA-UHFFFAOYNA-N
SMILES
OC1CN2CCC1CC2
Form
Crystals or powder or crystalline powder or fused/lumpy solid
Assay (Silylated GC)
≥98.0%
Identification (FTIR)
Conforms
Melting Point (clear melt)
219.0-229.0?C
Appearance (Color)
White to pale cream

Description

3-Quinuclidinol acts as a chiral building block for various antimuscarinic agents and other active pharmaceutical ingredients. It serves as a catalyst for condensation of methyl vinyl ketone with aldehydes. It is also used as a reagent for cleavage of beta-keto and vinylogous beta-keto esters. Further, it plays an important role as a synthon in the preparation of cholinergic receptor ligands and anesthetics. In addition to this, it is used in chemoselective alfa-iodination of acrylic esters through Morita-Baylis-Hillman reaction.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
3-Quinuclidinol acts as a chiral building block for various antimuscarinic agents and other active pharmaceutical ingredients. It serves as a catalyst for condensation of methyl vinyl ketone with aldehydes. It is also used as a reagent for cleavage of beta-keto and vinylogous beta-keto esters. Further, it plays an important role as a synthon in the preparation of cholinergic receptor ligands and anesthetics. In addition to this, it is used in chemoselective alfa-iodination of acrylic esters through Morita-Baylis-Hillman reaction.

Solubility
Soluble in water.

Notes
Incompatible with oxidizing agents.
RUO – Research Use Only

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