N-Benzyloxycarbonyl-L-proline, 98+%, Thermo Scientific Chemicals
N-Benzyloxycarbonyl-L-proline, 98+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

N-Benzyloxycarbonyl-L-proline, 98+%, Thermo Scientific Chemicals

Have Questions?
Change viewbuttonViewtableView
Quantity:
50 g
5 g
250 g
Catalog number B21672.18
also known as B21672-18
Price (USD)/ Each
164.00
-
Add to cart
Quantity:
50 g
Request bulk or custom format
Price (USD)/ Each
164.00
Add to cart
N-Benzyloxycarbonyl-L-proline, 98+%, Thermo Scientific Chemicals
Catalog numberB21672.18
Price (USD)/ Each
164.00
-
Add to cart
Chemical Identifiers
CAS1148-11-4
IUPAC Name(2S)-1-[(benzyloxy)carbonyl]pyrrolidine-2-carboxylate
Molecular FormulaC13H14NO4
InChI KeyJXGVXCZADZNAMJ-NSHDSACASA-M
SMILES[O-]C(=O)[C@@H]1CCCN1C(=O)OCC1=CC=CC=C1
View more
SpecificationsSpecification SheetSpecification Sheet
FormPowder or crystalline powder or crystals or granules
Optical Rotation-58° to -62° (c=1 in acetic acid)
Appearance (Color)White to cream
Assay (Aqueous acid-base Titration)≥98.0 to ≤102.0%
N-(Benzyloxycarbonyl)-L-proline is a potent inhibitor of prolidase; a specific peptidase that cleaves dipeptides with a C-terminal prolyl and hydroxylprolyl residue. It is also used in the synthesis of N-(L-Prolyl)-β-alanine which is a derivative of the naturally occurring beta amino acid β-Alanine.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N-(Benzyloxycarbonyl)-L-proline is a potent inhibitor of prolidase; a specific peptidase that cleaves dipeptides with a C-terminal prolyl and hydroxylprolyl residue. It is also used in the synthesis of N-(L-Prolyl)-β-alanine which is a derivative of the naturally occurring beta amino acid β-Alanine.

Solubility
Solubility in methanol, almost transparency.

Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only

General References:

  1. Anna Lupi, et al. CN-benzyloxycarbonyl-l-proline: An in vitro and in vivo inhibitor of prolidase.Biochim. Biophys. Acta.20051744(2), 157-163.
  2. Lidia De Luca, et al. An Easy and Convenient Synthesis of Weinreb Amides and Hydroxamates.J. Org. Chem.,200166(7), 2534-2537.