A product for proteomics research. Also used as a reagent in the preparation of nitric oxide-donating analogues of Sulindac (S699215), a non-steroidal anti-inflammatory drug that has the ability to prevent colon cancer.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
A product for proteomics research. Also used as a reagent in the preparation of nitric oxide-donating analogues of Sulindac (S699215), a non-steroidal anti-inflammatory drug that has the ability to prevent colon cancer.
Solubility
Soluble in chloroform and methanol.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- Andrew Nortcliffe; Alexander G. Ekstrom; James R. Black; James A. Ross; Fouad K. Habib; Nigel P. Botting; David O’Hagan. Synthesis and biological evaluation of nitric oxide-donating analogues of sulindac for prostate cancer treatment.Bioorganic & Medicinal Chemistry.201422(2), 756-761.
- Pasricha, P., et al. The effects of sulindac on colorectal proliferation and apoptosis in familial adenomatous polyposis.Gastroenterology.1995109(3), 994-998.