Sodium dichloroacetate finds medicinal application in removing warts and other skin growths. It is used as an antidote for lactic acidosis and in the treatment of stroke. It is studied as potential drugs, since it inhibits the enzyme pyruvate dehydrogenase kinase.
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Applications
Sodium dichloroacetate finds medicinal application in removing warts and other skin growths. It is used as an antidote for lactic acidosis and in the treatment of stroke. It is studied as potential drugs, since it inhibits the enzyme pyruvate dehydrogenase kinase.
Solubility
Soluble in water.
Notes
Moisture sensitive. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Agnoletto, C.; Brunelli, L.; Melloni, E.; Pastorelli, R.; Casciano, F.; Rimondi, E.; Rigolin, G. M.; Cuneo, A.; Secchiero, P.; Zauli, G. The anti-leukemic activity of sodium dichloroacetate in p53mutatedull cells is mediated by a p53-independent ILF3/p21 pathway. Oncotarget 2015, 6 (4), 2385-2396.
- Ji, B.; Tang, P.; Yan, K.; Sun, G. Catalytic actions of alkaline salts in reactions between 1, 2, 3, 4-butanetetracarboxylic acid and cellulose: II. Esterification. Carbohydr. Polym. 2015, 132, 228-236.