alpha-Toluenesulfonyl fluoride, 99%, Thermo Scientific Chemicals
alpha-Toluenesulfonyl fluoride, 99%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

alpha-Toluenesulfonyl fluoride, 99%, Thermo Scientific Chemicals

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5 g
1 g
25 g
Catalog number B22146.06
also known as B22146-06
Price (USD)/ Each
71.65
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79.90 
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Quantity:
5 g
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Price (USD)/ Each
71.65
Online exclusive
79.90 
Save 8.25 (10%)
Add to cart
alpha-Toluenesulfonyl fluoride, 99%, Thermo Scientific Chemicals
Catalog numberB22146.06
Price (USD)/ Each
71.65
Online exclusive
79.90 
Save 8.25 (10%)
-
Add to cart
Chemical Identifiers
CAS329-98-6
IUPAC Namephenylmethanesulfonyl fluoride
Molecular FormulaC7H7FO2S
InChI KeyYBYRMVIVWMBXKQ-UHFFFAOYSA-N
SMILESFS(=O)(=O)CC1=CC=CC=C1
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White
FormCrystals or powder or crystalline powder
Assay (GC)≥98.5%
Identification (FTIR)Conforms
Melting Point91-96?C
α-Toluenesulfonyl fluoride (PMSF) is used in the preparation of cell lysates to inhibit protein digestion. It is a widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
α-Toluenesulfonyl fluoride (PMSF) is used in the preparation of cell lysates to inhibit protein digestion. It is a widely used fatty acid amid hydrolase (FAAH) inhibitor for pretreatment of brain membrane preparations when testing CB1 receptor activity.

Solubility
Soluble in ether, benzene, anhydrous ethanol, methanol, 2- propane. Hydrolyses in water.

Notes
Moisture sensitive. Store away from strong oxidizing agents, amines, bases, water/ moisture. Store at 4°C
RUO – Research Use Only

General References:

  1. C Pinsky; A K Dua; F S LaBella. Phenylmethylsulfonyl fluoride (PMSF) given systemically produces naloxone-reversible analgesia and potentiates effects of beta-endorphin given centrally. Life Sciences. 1982, 31 (12-13), 1193-1196.
  2. G T James.Inactivation of the protease inhibitor phenylmethylsulfonyl fluoride in buffers. Analytical Biochemistry. 1978, 86 (2), 574-579.