Vitamin D3, 99%
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Vitamin D3, 99%
Thermo Scientific Chemicals

Vitamin D3, 99%

Vitamin D3, CAS # 67-97-0, also known as cholecalciferol, is a steroid hormone produced in the skin or obtained from dietary sources. It is an essential mediator of bone calcium metabolism.
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Catalog number B22524.06
also known as B22524-06
Price (USD)/ Each
147.65
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Quantity:
5 g
Request bulk or custom format
Price (USD)/ Each
147.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
173.00 
Save 25.35 (15%)
Add to cart
Vitamin D3, 99%
Catalog numberB22524.06
Price (USD)/ Each
147.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
173.00 
Save 25.35 (15%)
-
Add to cart
Chemical Identifiers
CAS67-97-0
IUPAC Name(1S,3E)-3-{2-[(1R,3aS,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol
Molecular FormulaC27H44O
InChI KeyQYSXJUFSXHHAJI-FVUVGDFOSA-N
SMILESCC(C)CCC[C@@H](C)[C@H]1CC[C@H]2\C(CCC[C@]12C)=C\C=C1/C[C@@H](O)CCC1=C
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)White
FormCrystals or powder or crystalline powder
Assay (HPLC)≥98.5%
Identification (FTIR)Conforms
Optical Rotation+108? ? 3? (c=0.8 in ethanol)
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Vitamin D3 is used as an essential mediator of intestinal calcium absorption and bone calcium metabolism. It is also used as a therapeutic vitamin. Further, it is used as a nutritional supplement and to fortify foods. In addition to this, it is used as pharmaceutical drug and used in the treatment of respiratory diseases involving chronic inflammation such as asthma.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• Vitamin D3 is a steroid hormone generated in the skin when the 7-dehydrocholesterol interacts with ultraviolet irradiation. It can also be found in several types of food for daily intake.
• Vitamin D3 binds to vitamin D receptors, thus modulating gene expression
Applications
• It presents in vitro antiproliferative and antimetastatic activities on breast, colon, and prostate cancer cells
RUO – Research Use Only

General References:

  1. Chakraborti, C. K. Vitamin D as a promising anticancer agent. Indian J Pharmacol. 2011 Apr;43(2):113-20. doi: 10.4103/0253-7613.77335.
  2. Meyer, O.; Dawson-Hughes, B.; Sidelnikov, E.; Egli, A.; Grob, D.; Staehelin, H. B.; Theiler, G.; Kressig, R. W.; Simmen, H. P.; Theiler, R.; Bischoff-Ferrari, H. A. Calcifediol versus vitamin D3 effects on gait speed and trunk sway in young postmenopausal women: a double-blind randomized controlled trial. Osteoporos Int. 2015, 26 (1), 373-381.
  3. Mehlig, L. M.; Garve, C.; Tauer, J. T.; Suttorp, M.; Bauer, A. Inhibitory effects of imatinib on vitamin D3 synthesis in human keratinocytes. Mol. Med. Rep. 2015, 11 (4), 3143-3147.