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4',7-Dihydroxyisoflavone, 97%, Thermo Scientific Chemicals
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Catalog number B22877.06
also known as B22877-06
Price (USD)/ Each
276.00
-
Quantity:
5 g
Price (USD)/ Each
276.00
4',7-Dihydroxyisoflavone, 97%, Thermo Scientific Chemicals
Catalog numberB22877.06
Price (USD)/ Each
276.00
-
Chemical Identifiers
CAS486-66-8
IUPAC Name7-hydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one
Molecular FormulaC15H10O4
InChI KeyZQSIJRDFPHDXIC-UHFFFAOYSA-N
SMILESOC1=CC=C(C=C1)C1=COC2=CC(O)=CC=C2C1=O
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Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder
Appearance (Color)White
Assay (HPLC)≥97.0%
4',7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4′,7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
Solubility
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
4′,7-Dihydroxyisoflavone is a phytoestrogen that is suggested to play a role in preventing hormone-induced cancers. It protects against oxidative damage in liver cells induced by 7,12-dimethylbenz[a]anthracene (DMBA). Catalase and superoxide dismutase activity, down-regulated by DMBA, was restored by daidzein.
Solubility
Insoluble in water. Soluble in DMSO (25 mg/ml), ethanol (2 mg/ml), DMF (10 mg/ml), and 1:10 DMSO:PBS (pH 7.2) (0.15 mg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
RUO – Research Use Only
General References:
- Eun Jeong Choi; Gun-Hee Kim. Hepatoprotective effects of daidzein against 7,12-dimetylbenz[a]anthracene-induced oxidative stress in mice. International Journal of Molecular Medicine. 2009, 23,(5), 659-664.
- N.Sathyamoorthy; T.T.Wang; J.M.Phang. Stimulation of pS2 expression by diet-derived compounds. Cancer Research. 1994, 54,(4), 957-961.